One of the most eagerly awaited events of the NFL offseason is almost here. The complete 2026 NFL schedule will be unveiled on Thursday, May 14, at 5 p.m. PT, providing full details on dates, kickoff times, and broadcast networks for every regular-season game.
The San Francisco 49ers’ 2026 opponents were largely determined through the league’s rotating scheduling formula. Along with their standard divisional matchups against NFC West rivals, the 49ers are scheduled to face all four teams from the NFC East and the AFC West this season.
The final three games on San Francisco’s slate were decided by the team’s third-place finish in the NFC West during the 2025 season. These positioning-based contests include games against other third-place finishers from the NFC North, AFC East, and NFC South.
One game is already locked in: the 49ers’ season opener on the international stage. San Francisco will take on the Los Angeles Rams in the NFL’s first-ever regular-season game held in Melbourne, Australia. The Week 1 matchup is scheduled for Thursday, Sept. 10, at 5:35 p.m. PT at the Melbourne Cricket Ground. Due to the 17-hour time difference, the game will kick off at 10:35 a.m. (AEST) in Melbourne on Friday, while airing live on the West Coast during Thursday evening.
The 49ers’ home opponents for the 2026 season include the Arizona Cardinals, Los Angeles Rams, Seattle Seahawks, Denver Broncos, Las Vegas Raiders, Philadelphia Eagles, Washington Commanders, Miami Dolphins, and Minnesota Vikings.
San Francisco’s road schedule features games against the Arizona Cardinals, Los Angeles Rams, Seattle Seahawks, Dallas Cowboys, Kansas City Chiefs, Los Angeles Chargers, New York Giants, and Atlanta Falcons.